Pat Fidopiastis, Ph.D.
B.S. CSU, Fullerton
M.A. CSU, Fullerton
Ph.D. University of Hawai'i, Manoa
- Cold-water fish pathogen V. salmonicida establishes a pathogenic relationship with salmon and trout.
- Luminous bacterium V. fischeri both establishes and maintains a symbiotic association with the Hawaiian sepiolid squid Euprymna scolopes.
- Phylogeny, physiology, and distribution of resident gut microbes within herbivorous marine fishes indigenous to the California coast.
- Symbiotic and pathogenic associations of marine Vibrio spp. with their animal hosts.
Further Research Details
Pat Fidopiastis is a microbiologist specializing in symbiotic and pathogenic associations of marine Vibrio spp. with their animal hosts. In particular, Dr. Fidopiastis studies the mechanisms by which the luminous bacterium V. fischeri both establishes and maintains a symbiotic association with the Hawaiian sepiolid squid Euprymna scolopes.
This association is emerging as a model for better understanding how Gram negative bacteria in general establish and maintain symbiotic and pathogenic associations with humans. The Fidopiastis lab also studies the mechanisms by which the cold-water fish pathogen V. salmonicida establishes a pathogenic relationship with salmon and trout.
This lab uses the latest tools in molecular biology to identify, isolate, and characterize Vibrio genes whose products might be involved in their symbiotic or pathogenic niches. The Fidopiastis lab has begun an in-depth analysis of the phylogeny, physiology, and distribution of resident gut microbes within herbivorous marine fishes indigenous to the California coast.
- Luminescence regulation in marine vibrios
- Pathogenic and mutualistic interactions between bacteria and marine animals
Stoudenmire J.L., Black M., Fidopiastis P.M., Stabb E.V. (2019) Mutagenesis of Vibrio fischeri and Other Marine Bacteria Using Hyperactive Mini-Tn5 Derivatives. In: Ricke S., Park S., Davis M. (eds) Microbial Transposon Mutagenesis. Methods in Molecular Biology, vol 2016. Humana, New York, NY
Yim, S., Clark, C.M., Peters, T., Prodanov, V., and P.M. Fidopiastis. ROV-based Tracking of a Shallow Water Nocturnal Squid. Proc. of the OCEANS 2013 Conference (OCEANS 2013)
Fidopiastis PM, Rader BA, Gerling D, Gutierrez N, Watkins K, Frey M, Nyholm SV, Whistler CA. 2012. Characterization of a Vibrio fischeri aminopeptidase and evidence for its influence on an early state of squid colonization. J. Bacteriol. Aug/194(15): 3995-4002.
Nelson EJ, Tunsjø HS, Fidopiastis PM, Sørum H, Ruby EG. 2007. A novel lux operon in the cryptically bioluminescent fish pathogen Vibrio salmonicida is associated with virulence. Appl. Environ. Micro. 73: 1825-1833.
Fidopiastis PM, Bezdek DJ, Kandel JS, Horn MH. 2006. Characterizing the resident, fermentative microbial consortium in the hindgut of the temperate-zone herbivorous fish, Hermosilla azurea (Teleostei: Kyphosidae). Mar. Biol. 148: 631-642.
Fidopiastis PM, Miyamato CM, Jobling MG, Meighen EA, Ruby EG. 2002. LitR, a new transcriptional activator in Vibrio fischeri, regulates luminescence and symbiotic light organ colonization. Mol. Microbiol. 45: 131-143.
Fidopiastis PM. 2001. Benign infection of sepiolid squids by luminous Vibrio species: model systems for understanding environmental and genetic factors that regulate bacteria-host interaction. Ph.D. Dissertation, Univ. of Hawai'i, Manoa.
Fidopiastis PM, Sørum H, Ruby EG. 1999. Cryptic luminescence in the cold-water fish pathogen Vibrio salmonicida. Arch. Microbiol. 171: 205-209.
Fidopiastis PM, von Boletzky S, Ruby EG. 1998. A new niche for Vibrio logei, the predominant light organ symbiont of the Mediterranean sepiolid squids Sepiola affinis and S. robusta. J. Bacteriol. 180: 59-64.
Fidopiastis PM, von Boletzky S. 1998. Identification and physiological characterization of light organ symbionts of Mediterranean sepiolod squids. Pacific Science vol. 52.